What does Schedule S prescribe under D and C Act 1940?
💡Correct Answer: Option B (Standards for Cosmetics)
Under the Drugs and Cosmetics Rules, 1945, Schedule S prescribes the statutory standards, testing specifications, and quality limits for Cosmetics manufactured in India.
Q2
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsNational Research Institutes
Indian Veterinary Research Institute is situated at ......
💡Correct Answer: Option C (Izatnagar)
The Indian Veterinary Research Institute (ICAR-IVRI), established in 1889, is located at Izatnagar, Bareilly in Uttar Pradesh.
Q3
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsD&C Act Schedule J
List of diseases and ailments which a drug may not claim to prevent or cure is covered under .............
💡Correct Answer: Option C (Schedule J)
Schedule J of the D&C Rules lists diseases and ailments (such as Cancer, AIDS, Diabetes, Blindness) which a drug may not claim to prevent or cure.
Q4
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsDTAB Constitution
DTAB has ______ Ex-officio members
💡Correct Answer: Option D (Eight)
Under Section 5 of the D&C Act 1940, the Drugs Technical Advisory Board (DTAB) consists of 18 members in total, out of which exactly 8 are Ex-Officio Members (including DGHS, DCGI, CDL Director, CRI Kasauli Director, IVRI Director, Central Drug Research Institute Director, President MCI, and President PCI).
Q5
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsSchedule X Psychotropic Substances
Examples of Schedule X except ______
💡Correct Answer: Option A (Analgin)
Schedule X covers potent psychotropic and habit-forming barbiturates/CNS depressants (Amobarbital, Pentobarbital, Cyclobarbital). Analgin (Metamizole) is an NSAID/analgesic and is not a Schedule X drug.
Q6
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsMisbranded Drugs Definition
If it is so coloured, coated, powdered or polished that damage is concealed or if it is made to appear of better or greater therapeutic value than it really is;
💡Correct Answer: Option C (Misbranded drug)
Under Section 17 of the Drugs and Cosmetics Act 1940, a drug is deemed to be Misbranded if it is so coloured, coated, powdered, or polished that damage is concealed, or if it is made to appear of greater therapeutic value than it really is.
Q7
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsD&C Act License Forms
Give the form no. of Licence required for retail sale of drugs other than Schedule C, C1, X
💡Correct Answer: Option B (Form 20)
Form 20 is the statutory license granted for the retail sale of general allopathic drugs other than those specified in Schedules C, C1, and X (Form 21 is for C/C1; Form 20F is for Schedule X).
Q8
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsLoan License Forms
Application for the grant or renewal of loan license shall be made in ______
💡Correct Answer: Option A (Form 24A)
Application for the grant or renewal of a Loan License to manufacture for sale of drugs other than those specified in Schedule C/C1 is submitted in Form 24A.
Q9
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsDrug Import Rules
The application to import drug as part of bonafide luggage is made to the licensing authority in .......
💡Correct Answer: Option C (Form 12B)
Under Rule 36 of the D&C Rules, an application for a permit to import small quantities of drugs for personal use as part of bonafide passenger luggage is made in Form 12B (permit issued in Form 12BA).
Q10
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsStatutory Education Acts
University Grants Commission established under section 4 of ______
💡Correct Answer: Option B (UGC Act, 1956)
The University Grants Commission (UGC) of India was formally established as a statutory body under Section 4 of the University Grants Commission Act, 1956.
Q11
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsPharmacy Act Central Register
Register of Pharmacist maintained by the Central Council under ______
💡Correct Answer: Option D (Section 15A)
Under Section 15A of the Pharmacy Act, 1948, the Central Council (PCI) maintains the Central Register of Pharmacists containing the names of all registered pharmacists across India.
Q12
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsPCI Council Composition
In the constitution of Central Council, Six members nominated by ______
💡Correct Answer: Option B (Central Government)
Under Section 3(a) of the Pharmacy Act 1948, six members (of whom at least four shall be persons possessing a degree or diploma in pharmacy/pharmaceutical chemistry) are nominated by the Central Government.
Q13
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsPCI Reconstitution
The Pharmacy Council of India is reconstituted by the Central Government every ______
💡Correct Answer: Option B (Five years)
Under Section 3 of the Pharmacy Act 1948, the Pharmacy Council of India is reconstituted by the Central Government every five years.
Q14
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsDMRA 1954 Penalties
Penalty for whoever contravenes any of the provision of D.M.R.(O.A) Act, 1954 in case of first conviction ______
💡Correct Answer: Option B (Imprisonment 6 months or with fine or with both)
Under Section 7(a) of the Drugs and Magic Remedies (Objectionable Advertisements) Act 1954, a first conviction is punishable with imprisonment extending to 6 months, or with fine, or with both (second conviction up to 1 year).
Q15
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsCode of Pharmaceutical Ethics
Who formulated the code of ethics for the Pharmacy Profession?
💡Correct Answer: Option B (Pharmacy Council of India)
The Pharmacy Council of India (PCI) formulated the official Code of Pharmaceutical Ethics governing pharmacists' relationships to their job, trade, medical profession, and profession.
Q16
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsPharmaceutical Ethics Categories
Hawking of drugs is a part of ethics related to ______
💡Correct Answer: Option A (Pharmacist in relation to his trade)
Under the PCI Code of Pharmaceutical Ethics, prohibition of hawking (canvassing/peddling drugs in public streets) is covered under 'Pharmacist in relation to his trade'.
Q17
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsPoisons Act Import Regulations
Import of poison under Poison Act, 1919 regulated by ______
💡Correct Answer: Option B (Central Government)
Under Section 2 of the Poisons Act, 1919, the Central Government is statutory authorized to regulate the importation of poisons into India.
Q18
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsNPPA Pricing Regulatory Body
The provisions of DPCO are implemented and enforced by ______
💡Correct Answer: Option B (NPPA)
The National Pharmaceutical Pricing Authority (NPPA), an attached office of the Department of Pharmaceuticals, enforces and monitors the Drugs (Prices Control) Order.
Q19
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsDPCO Pricing Formulas
For calculation of price of bulk drugs a return of 12% is allowed on ______ costing
💡Correct Answer: Option B (Long term marginal)
Under DPCO bulk drug pricing formulas, pre-tax return of 14% on net worth or 12% on Long Term Marginal Costing is allowed for calculating bulk drug ceiling prices.
Q20
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsDPCO Rate of Return
For production from basic stage post tax return of ______ on net worth is considered.
💡Correct Answer: Option C (18%)
Under national pharmaceutical pricing formulas for active pharmaceutical ingredients manufactured from the basic chemical stage, an incentive post-tax return of 18% on net worth is permitted.
Q21
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsMTP Safety Limits
Medical Termination of pregnancy is safe up to ______
💡Correct Answer: Option A (12 weeks)
Medical Termination of Pregnancy (MTP) is medically safest during the first trimester (up to 12 weeks of gestation).
Q22
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsMTP Penalties
Penalty for termination of pregnancy by a person who is not a RMP
💡Correct Answer: Option B (Rigorous imprisonment for two to seven years)
Under Section 5(2) of the Medical Termination of Pregnancy Act, 1971, termination of pregnancy by any person who is not a registered medical practitioner is punishable with rigorous imprisonment for a term of two to seven years.
Q23
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsIAEC Full Form
The full form of IAEC is ______
💡Correct Answer: Option A (Institutional Animal Ethics Committee)
IAEC stands for Institutional Animal Ethics Committee, established in every institution conducting animal experimentation under CPCSEA guidelines.
Q24
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsAnimal Experimentation Approval
Name the local body which allows experiments on small animals.
💡Correct Answer: Option A (IAEC)
The Institutional Animal Ethics Committee (IAEC) is the statutory institutional body empowered to review and permit research protocols involving small laboratory animals (rodents, rabbits).
Q25
Pharmaceutical Jurisprudence, Drug Acts & Regulatory AffairsTrade Marks Act 1999
Trade Marks Registry has been established under section of the Trade Marks Act, 1999 to provide for registration and better protection of trademarks for goods and services
💡Correct Answer: Option D (Section 5(1))
Section 5(1) of the Trade Marks Act, 1999 provides for the statutory establishment of the Trade Marks Registry headed by the Controller-General of Patents, Designs and Trade Marks.
Q26
Pharmaceutics, Dosage Forms & BiopharmaceuticsTablet Defects (Sticking)
Excessive moisture present in tablet granules is responsible for
💡Correct Answer: Option C (Sticking)
Excessive residual moisture in dried granules causes the formulation to adhere to the die wall and punch faces during compression, resulting in Sticking (and picking).
Q27
Pharmaceutics, Dosage Forms & BiopharmaceuticsAngle of Repose & Flowability
What is the range of angle of repose for excellent flowing property of powder?
💡Correct Answer: Option A ($25^\circ\text{--}30^\circ$)
According to pharmacopoeial standards: An angle of repose (θ) between 25∘–30∘ indicates Excellent powder flow; 31∘–35∘ indicates Good; >50∘ indicates Very Poor.
Q28
Pharmaceutics, Dosage Forms & BiopharmaceuticsTablet Defects (Mottling)
Mottling in tablets means
💡Correct Answer: Option C (Unequal distribution of colour on a tablet)
Mottling is a visual tablet defect characterized by an unequal, non-uniform distribution of colour on the tablet surface due to dye migration.
Q29
Pharmaceutics, Dosage Forms & BiopharmaceuticsRenal Clearance Definition
The ratio of rate of urinary excretion to plasma drug concentration is
💡Correct Answer: Option B (Renal Clearance)
Renal Clearance (ClR) is defined as: ClR=Plasma drug concentration (Cp)Rate of urinary drug excretion (dXu/dt).
Q30
Pharmaceutics, Dosage Forms & BiopharmaceuticsEmulsion Formulation Ratios
For the preparation of primary emulsion containing fixed oil, the ratio of fixed oil: water :gum is
💡Correct Answer: Option D (Ratio 4:2:1)
The classic Continental/Dry Gum method uses a standard ratio for primary emulsion: Fixed Oils = 4 : 2 : 1 (Oil:Water:Gum); Mineral Oils = 3 : 2 : 1; Volatile Oils = 2 : 2 : 1.
Q31
Pharmaceutics, Dosage Forms & BiopharmaceuticsBioequivalence Study Requirements
Bioequivalence studies are necessary:
💡Correct Answer: Option D (Fixed dose combination products with systemic action)
In vivo bioequivalence testing is mandatory for multi-active Fixed Dose Combination (FDC) generic formulations with systemic action to demonstrate therapeutic equivalence.
Q32
Pharmaceutics, Dosage Forms & BiopharmaceuticsUSP Dissolution Apparatus Types
Pharmaceutics, Dosage Forms & BiopharmaceuticsImmunology of Vaccines
Live attenuated vaccines are better immunizing agents because:
💡Correct Answer: Option C (Replication of organism in a live attenuated vaccine increases the stimulation of the immune system and a lower dose is often required.)
Live attenuated vaccines mimic natural subclinical infection: the attenuated pathogen actively replicates in host tissues, providing sustained antigenic presentation, robust humoral and cell-mediated immunity with single lower doses.
Q34
Pharmaceutics, Dosage Forms & BiopharmaceuticsPharmacokinetics Loading Dose
The loading dose of a drug is determined on the basis of:
💡Correct Answer: Option D (Apparent volume of distribution and desired drug concentration in plasma.)
Loading dose (DL) is calculated as: DL=Vd×Ctarget (where Vd is the apparent volume of distribution and Ctarget is the target therapeutic steady-state plasma concentration).
Q35
Pharmaceutics, Dosage Forms & BiopharmaceuticsSuspension Formulation Chemistry
Suspending agents are added to suspension for
💡Correct Answer: Option B (Increasing the zeta potential)
Suspending and deflocculating agents increase the medium viscosity and adjust the surface electrical charge, Increasing the Zeta Potential to prevent rapid irreversible cake formation.
Q36
Pharmaceutics, Dosage Forms & BiopharmaceuticsICH Stability Testing Guidelines
Guidelines for stability testing of drugs are given by
💡Correct Answer: Option C (Both)
International harmonization guidelines for drug stability testing (Q1A-Q1F) are formulated jointly by the International Council for Harmonisation (ICH) and adopted by regulatory authorities including the USFDA and CDSCO (Both).
Q37
Pharmaceutics, Dosage Forms & BiopharmaceuticsParenteral Particulate Matter Standards
A 500 ml infusion bag of a formulation complies the particulate matter test if the average number of particles greater than or equal to 10 microns, present in the units does not exceed:
💡Correct Answer: Option A (25 particles per ml)
Under USP <788> and IP particulate matter standards for large volume parenterals (>100 mL), the formulation passes if the average count does not exceed 25 particles/mL ≥10μm (and 3 particles/mL ≥25μm).
Q38
Pharmaceutics, Dosage Forms & BiopharmaceuticsHEPA Filter Validation
DOP or smoke test(Dioctyl phthalate test)is used for
💡Correct Answer: Option D (Determining HEPA filter integrity)
The Dioctyl Phthalate (DOP) aerosol challenge test (or PAO test) is the standard validation test used to verify the filtration efficiency and leak-free integrity of cleanroom HEPA filters (99.97% retention at 0.3μm).
Q39
Pharmaceutics, Dosage Forms & BiopharmaceuticsNovel Drug Delivery Systems (Liposomes)
A drug delivery system which is composed of phospholipids that spontaneously form a multilamellar concentric bilayer vesicles with layers of aqueous media separating the lipid layers is
💡Correct Answer: Option B (Liposomes)
Liposomes are microscopic vesicular delivery systems formed spontaneously by natural phospholipids organized into concentric spherical lipid bilayers enclosing aqueous compartments.
Q40
Pharmaceutics, Dosage Forms & BiopharmaceuticsMicroencapsulation Techniques
Microencapsulation achieved by
💡Correct Answer: Option B (Co-acervation phase separation)
Coacervation-Phase Separation (thermal change, non-solvent addition, or complex coacervation) is a premier physical-chemical method for microencapsulating pharmaceutical drug cores.
Q41
Pharmaceutics, Dosage Forms & BiopharmaceuticsOphthalmic Ointments
Ophthalmic ointments are primarily anhydrous and contain mineral oil and white petrolatum as the base ingredients.______
💡Correct Answer: Option A (The Statement is Correct)
Pharmacopoeial sterile ophthalmic ointment bases are anhydrous lipophilic systems formulated with white soft paraffin (petrolatum), liquid paraffin (mineral oil), and wool fat.
Q42
Pharmaceutics, Dosage Forms & BiopharmaceuticsPharmacokinetic Parameters
What does "Cmax" represent in pharmacokinetics?
💡Correct Answer: Option C (Maximum concentration of drug in plasma)
Cmax represents the Maximum (peak) concentration of a drug observed in the systemic blood plasma circulation following administration.
Q43
Pharmaceutics, Dosage Forms & BiopharmaceuticsSuppository Displacement Value
What is the term used for the displacement value in suppository formulation?
💡Correct Answer: Option A (The volume of base displaced by the drug)
The Displacement Value is the number of parts by weight of a medicament that displaces 1 part by weight of the suppository base (representing the volume of base displaced by the drug).
Q44
Pharmaceutics, Dosage Forms & BiopharmaceuticsGriffin's HLB Scale Matching
Match Property of Surfactant to HLB Values in range: Property: 1. Emulsifying Agent (W/O) 2. Wetting Agent (O/W) 3. Antifoaming 4. Solubilizer
HLB Values in range: i. 15 to 20 ii. 1 to 3 iii. 8 to 18 (or 7 to 9) iv. 3 to 6
Choose the Correct Option:
💡Correct Answer: Option A (1-iv, 2-iii, 3-ii, 4-i)
On Griffin's HLB scale: 1 -> iv (W/O Emulsifier: 3 to 6), 2 -> iii (Wetting agent: 7 to 9 / O/W Emulsifier: 8 to 16), 3 -> ii (Antifoaming agent: 1 to 3), 4 -> i (Solubilizer: 15 to 20). Correct match: 1-iv, 2-iii, 3-ii, 4-i.
Q45
Pharmaceutics, Dosage Forms & BiopharmaceuticsGelatin Chemistry
Isoelectric point of type A gelatine is
💡Correct Answer: Option C (pH 9.0)
Type A gelatin (derived from acid-treated pig skin collagen) has an Isoelectric Point between pH 7.0–9.0 (typically pH 9.0), whereas Type B gelatin (alkali-treated) has an isoelectric point of pH 4.7–5.0.
Q46
Pharmaceutics, Dosage Forms & BiopharmaceuticsOphthalmic Physiology
pH of Lachrymal Fluid is ______
💡Correct Answer: Option D (pH 7.4)
The physiological pH of human tears (lachrymal fluid) is approximately 7.4 (ranging from 7.2 to 7.6), identical to normal blood plasma pH.
Q47
Pharmaceutics, Dosage Forms & BiopharmaceuticsPharmacopoeial Storage Conditions
The Statement 'store in a cool place' as per IP means
💡Correct Answer: Option C (Store at any temperature between $8^\circ\text{C to }25^\circ\text{C}$)
According to Indian Pharmacopoeia storage conditions: 'Cold' = 2∘extto8∘extC; 'Cool' = 8∘extto25∘extC; 'Room temperature' = 25∘extto30∘extC; 'Warm' = 30∘extto40∘extC.
Q48
Pharmaceutics, Dosage Forms & BiopharmaceuticsDissolution Kinetics
Which of the following equation gives the rate of drug dissolution from a tablet?
💡Correct Answer: Option C (Noyes Whitney equation)
The Noyes-Whitney equation (dtdC=hD⋅A(Cs−C)) governs the diffusion-controlled dissolution rate of solid drugs in dissolution media.
Q49
Pharmaceutics, Dosage Forms & BiopharmaceuticsPharmaceutical Polymers Matching
Various polymers used in pharmacy are given. Match them with respective monomer: Polymer: 1. Carbopol 2. Eudragits 3. Polyethylene 4. Polycarbonate
Monomer: i. (Bis-phenol + phosgene) ii. Ethylene iii. Methacrylate ester iv. Acrylic Acid
Choose the Correct Option:
💡Correct Answer: Option D (1-iv, 2-iii, 3-ii, 4-i)
1 -> iv (Carbopol: crosslinked Acrylic Acid polymer), 2 -> iii (Eudragit: Methacrylic acid/methacrylate copolymer), 3 -> ii (Polyethylene: Ethylene monomer), 4 -> i (Polycarbonate: Bisphenol A + Phosgene). Correct match: 1-iv, 2-iii, 3-ii, 4-i.
Q50
Pharmaceutics, Dosage Forms & BiopharmaceuticsLyophilization of Biologicals
Drying of blood products and enzyme based preparation is carried out by:
💡Correct Answer: Option C (Lyophilization)
Thermolabile biological preparations, blood products, proteins, and enzymes are dehydrated using Lyophilization (Freeze-drying / sublimation under vacuum).
Q51
Pharmaceutical Analysis, Limit Tests & Quality ControlSterility Testing Media
Which of the following culture media is used to detect fungi in sterility testing.
💡Correct Answer: Option A (Soybean casein Digest medium)
Under IP/USP sterility testing, Fluid Thioglycollate Medium (FTM) is used primarily for anaerobic/aerobic bacteria, while Soybean-Casein Digest Medium (SCDM / TSB) incubated at 20ext−−25∘extC is used for detecting fungi and aerobic bacteria.
As per IP, temperature range for incubation in sterility testing is
💡Correct Answer: Option B ($20\text{--}25^\circ\text{C}$)
According to Indian Pharmacopoeia sterility testing monographs, Soybean Casein Digest Medium for fungi is incubated at 20ext−−25∘extC (and FTM for bacteria at 30ext−−35∘extC).
Q53
Pharmaceutical Analysis, Limit Tests & Quality ControlRabbit Pyrogen Test
Animals commonly used in pyrogen testing
💡Correct Answer: Option A (Rabbit)
Healthy mature Albino Rabbits are statutory mandated for the in vivo Rabbit Pyrogen Test due to their reproducible hyperthermic fever response matching human pyrogen sensitivity.
Q54
Pharmaceutical Analysis, Limit Tests & Quality ControlLimit Test Chemistry
Assertion: Thioglycollic acid is added in limit test of heavy metals Reason: Thioglycollic acid acts as reducing and complexing agent Which of the following is correct?
💡Correct Answer: Option C (Both A and R are true)
In the limit test for iron (and select heavy metals), Thioglycolic acid reduces ferric (Fe3+) ions to ferrous (Fe2+) and forms a stable reddish-purple coordination complex with iron in ammoniacal medium (Both A and R are true).
Q55
Pharmaceutical Analysis, Limit Tests & Quality ControlLimit Test for Lead (Dithizone)
Lead reacts with dithizone to give ______ complex
💡Correct Answer: Option A (Violet)
In the pharmacopoeial limit test for Lead, lead ions (Pb2+) react with dithizone (diphenylthiocarbazone) reagent in ammoniacal cyanide solution to form a distinctive violet-red / plum-violet lead dithizonate complex.
Q56
Pharmaceutical Analysis, Limit Tests & Quality ControlGutzeit Limit Test for Arsenic
Arsine gas reacts with ______ to give yellow stain
💡Correct Answer: Option A ($\text{HgCl}_2$)
In the Gutzeit limit test for Arsenic, generated arsine gas (AsH3) reacts with Mercuric Chloride (HgCl2) test paper to produce a yellow-to-brown stain of mercuric arsenide.
Q57
Pharmaceutical Analysis, Limit Tests & Quality ControlStokes Shift in Fluorimetry
In fluorimetry, the wavelength of fluorescent radiation ______
💡Correct Answer: Option B (Is more than wavelength of absorbed radiation)
Due to Stokes Shift (energy loss via non-radiative vibrational relaxation in the excited state), emitted fluorescence photons have lower energy and therefore a Longer (higher) Wavelength than the absorbed excitation radiation (λem>λabs).
Which one of the following is an example of wavelength selector in UV visible spectroscopy
💡Correct Answer: Option B (Monochromator)
A Monochromator (comprising entrance slit, dispersion prism/diffraction grating, and exit slit) functions as the wavelength selector isolating narrow monochromatic bands in UV-Vis spectrophotometers.
Paracetamol and ibuprofen combination can be analyzed by using the following method.
💡Correct Answer: Option C (Simultaneous Equation method)
Binary combination formulations (Paracetamol + Ibuprofen) with overlapping UV absorption spectra are quantitatively resolved without chemical separation using the Simultaneous Equation Method (Vierordt's two-wavelength method).
Assertion: On increasing pH phenol shows bathochromic shift Reason: Phenol exists in phenoxide ion, which shows more absorption increasing wavelength. Which of the following is correct?
💡Correct Answer: Option C (Both A and R are true)
Both A and R are true: Deprotonation of phenol at alkaline pH produces the phenoxide anion, where the unshared electron pair on oxygen conjugates more strongly with the aromatic π-system, lowering the π−>π∗ excitation energy and causing a red shift (Bathochromic shift to longer λmax).
Q62
Pharmaceutical Analysis, Limit Tests & Quality ControlBeer-Lambert Law
Beer Lambert 's law gives the relation between which of the following?
💡Correct Answer: Option C (Energy absorption and concentration)
The Beer-Lambert Law (A=ε⋅b⋅c) mathematically relates monochromatic radiant Energy Absorption (absorbance) to the molar Concentration of absorbing species and optical path length.
Q63
Pharmaceutical Analysis, Limit Tests & Quality ControlClinical Applications of Turbidimetry
What is the main clinical use of Turbidimetry
💡Correct Answer: Option D (Determination of concentration of total proteins in biological fluids.)
Turbidimetry is clinically employed for the rapid quantitative determination of Total Protein concentrations in biological fluids (CSF, urine, plasma) and immunoturbidimetric assays.
When molecules are excited in visible region, which lamp is used.
💡Correct Answer: Option C (Tungsten lamp)
A Tungsten-Halogen filament lamp provides a stable continuous emission spectrum across the Visible and near-infrared regions (320–1100 nm), whereas Deuterium lamps are used for the UV range (190–380 nm).
What is the primary principle of the Karl Fischer Titration?
💡Correct Answer: Option B (To determine the moisture content of a given analyte)
Karl Fischer Titration is the specific electrochemical redox iodometric method used to determine trace Water / Moisture Content in pharmaceutical chemicals.
Listed below are substances which are assayed by methods in i to iii. Match them: Substance: 1. Ascorbic Acid 2. Thiamine Hydrochloride 3. Pyridoxine Hydrochloride
Method: i. Spectrophotometry ii. Fluorimetry iii. Ceric ammonium sulphate oxidation
Choose the Correct Option:
💡Correct Answer: Option A (1-iii, 2-ii, 3-i)
1 -> iii (Ascorbic Acid: redox titration using Ceric ammonium sulphate), 2 -> ii (Thiamine HCl: oxidation to fluorescent thiochrome measured by Fluorimetry), 3 -> i (Pyridoxine HCl: Spectrophotometry). Correct match: 1-iii, 2-ii, 3-i.
Q68
Pharmaceutics, Dosage Forms & BiopharmaceuticsPharmaceutical Solutions
The alcoholic concentration of spirit is ______ than aromatic waters
💡Correct Answer: Option C (More)
Spirits are alcoholic or hydroalcoholic solutions containing high volatile oil concentrations (>60–80% alcohol), whereas Aromatic Waters are dilute aqueous solutions containing only saturated traces of volatile oils.
Q69
Pharmaceutical Analysis, Limit Tests & Quality ControlNMR Chemical Shift Principles
The chemical shift value is
💡Correct Answer: Option B (Not proportional to field strength)
In NMR spectroscopy, the Chemical Shift (δ in parts per million / ppm) is dimensionless and strictly Independent of (not proportional to) the operating magnetic field strength (B0), ensuring standardized reporting across different NMR instruments.
Q70
Pharmaceutical Analysis, Limit Tests & Quality ControlElectronic Transitions in UV-Vis
Energy absorbed in U.V. region produces changes in the
💡Correct Answer: Option C (The electronic energy of the molecule)
Absorption of ultraviolet and visible electromagnetic radiation (200–800 nm) possesses sufficient quantum energy to promote valence electrons from bonding/non-bonding ground state orbitals to anti-bonding orbitals (Electronic Energy transitions).
Q71
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsBenzodiazepines
Which of the following drug belongs to the class of benzodiazepine
💡Correct Answer: Option B (Diazepam)
Diazepam is a prototype long-acting central nervous system depressant belonging to the 1,4-benzodiazepine class.
Q72
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsNSAID Structures and Brand Names
Choose the correct brand name for the following drug: [Chemical Structure: 2-(4-isobutylphenyl)propanoic acid]
💡Correct Answer: Option A (Brufen)
The chemical structure shown is 2-(4-isobutylphenyl)propanoic acid, universally known by the generic name Ibuprofen, marketed under the famous brand name Brufen.
Q73
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsBeta-Blocker Synthesis
Which of the following drug is prepared from 1-naphthol?
💡Correct Answer: Option C (Propranolol)
Propranolol, a prototype non-selective beta-adrenergic blocker, is industrially synthesized via base-catalyzed reaction of 1-naphthol with epichlorohydrin followed by ring opening with isopropylamine.
Q74
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsCardiac Glycosides SAR
In digitalis glycoside C17 position of steroidal ring is substituted by
💡Correct Answer: Option A ($\alpha-\beta$ unsaturated five membered lactone ring)
In cardenolides (digitalis glycosides like Digitoxin and Digoxin), the C-17 position of the cyclopentanoperhydrophenanthrene steroidal core carries an α,β-unsaturated 5-membered lactone (butenolide) ring.
Q75
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsDrug Heterocyclic Rings Matching
Match the columns: Drug: i. Astemizole ii. Diethyl stilbesterol iii. Indomethacin iv. Diltiazem
Ring / Group: 1. Phenol ring 2. Indole ring 3. Benzothiazepine ring 4. 1,3-benzodiazole ring
Choose the Correct Option:
💡Correct Answer: Option A (i-4, ii-1, iii-2, iv-3)
i -> 4 (Astemizole: contains 1,3-benzodiazole / benzimidazole ring), ii -> 1 (Diethylstilbestrol: synthetic non-steroidal estrogen with phenolic rings), iii -> 2 (Indomethacin: indole-3-acetic acid derivative), iv -> 3 (Diltiazem: 1,5-benzothiazepine calcium channel blocker). Correct match: i-4, ii-1, iii-2, iv-3.
Q76
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsAntihypertensive Pharmacology
Assertion: Clonidine is used as antihypertensive drug Reason: Clonidine is centrally acting α2 agonist Which of the following is correct?
💡Correct Answer: Option D (Both A and R are true)
Both Assertion and Reason are true and Reason explains Assertion: Clonidine stimulates presynaptic α2-adrenergic receptors in the brainstem (nucleus tractus solitarii), inhibiting sympathetic outflow and reducing vascular tone and blood pressure.
Q77
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsBenzodiazepine Synthesis
Chlordiazepoxide is synthesized from
💡Correct Answer: Option B (p-chloroaniline and benzoyl chloride)
Chlordiazepoxide (the first synthesized benzodiazepine) is prepared starting from the reaction of 2-amino-5-chlorobenzophenone (derived from p-chloroaniline and benzoyl chloride) with hydroxylamine and chloroacetyl chloride.
Q78
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsDrug Classifications
Identify wrong pair
💡Correct Answer: Option D (Paracetamol - narcotic analgesic)
Paracetamol (Acetaminophen) is a non-opioid, non-narcotic antipyretic analgesic (Pair D is completely wrong).
Q79
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsAntiarrhythmic Drug Synthesis
Listed are some of the drug intermediates. Choose the correct one for the synthesis of procainamide
💡Correct Answer: Option C (p-nitrobenzoyl chloride and diethylamino ethylamine)
Procainamide is synthesized by reacting p-nitrobenzoyl chloride with N,N-diethylethylenediamine (diethylaminoethylamine), followed by catalytic reduction of the aromatic nitro group to an amine.
Q80
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsBenzodiazepine Metabolism
Assertion: Oxazepam is a short acting sedative Reason: Oxazepam belongs to the class of benzodiazepine Which of the following is correct?
💡Correct Answer: Option D (Both A and R are true, but reason is not the correct explanation of assertion)
Both Assertion and Reason are true: Oxazepam is indeed a short-to-intermediate acting sedative-hypnotic, and it belongs to the benzodiazepine class. However, its short duration of action is specifically due to direct Phase II glucuronide conjugation at its 3-hydroxy group (lack of active metabolites), not simply because it is a benzodiazepine. Choice D.
Q81
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsCommercial Pharmaceutical Brands Matching
Match the columns: Brand: i. Viagra ii. I pill iii. Omnacortil iv. Primacort
💡Correct Answer: Option A (i-4, ii-1, iii-2, iv-3)
i -> 4 (Viagra: Sildenafil), ii -> 1 (I-pill: Levonorgestrel emergency contraceptive), iii -> 2 (Omnacortil: Prednisolone), iv -> 3 (Primacort: Hydrocortisone sodium succinate). Correct match: i-4, ii-1, iii-2, iv-3.
Q82
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsAtypical Antipsychotics Pharmacology
Assertion: Risperidone shows lower incidences of extra pyramidal side effects Reason: Risperidone has high affinity for 5HT2A receptors as compared with D2 receptors. Which of the following is correct?
💡Correct Answer: Option C (Both A and R are true, but reason is the correct explanation of assertion)
Both Assertion and Reason are true, and the Reason correctly explains the Assertion: Atypical antipsychotics like Risperidone exhibit a high 5-HT2A/D2 receptor affinity ratio, where serotonin antagonism enhances dopamine release in the nigrostriatal pathway, markedly reducing Extrapyramidal Side Effects (EPS).
Q83
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsTricyclic Antidepressants
Identify tricyclic antidepressant
💡Correct Answer: Option C (Both A and B)
Both Imipramine (dibenzazepine) and Amitriptyline (dibenzocycloheptadiene) are classic prototypical Tricyclic Antidepressants (TCAs).
Q84
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsSedatives and Hypnotics
A drug that produce sleep is termed as
💡Correct Answer: Option B (Hypnotic)
A Hypnotic is a pharmacological central nervous system depressant agent administered specifically to induce, facilitate, and maintain normal physiological sleep.
Q85
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsOpioid Actions and Side Effects
Which of the following action is not associated with morphine?
💡Correct Answer: Option C (Diarrhea)
Morphine causes profound constipation (decreased peristalsis, spasm of sphincters), NOT diarrhea.
Q86
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsNon-Selective NSAIDs
Which of the following drug is nonselective COX inhibitor.
💡Correct Answer: Option D (All of the above)
Sulindac (indene derivative), Mefenamic acid (fenamate), and Piroxicam (oxicam) are all non-selective inhibitors of both COX-1 and COX-2 enzymes (All of the above).
Q87
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsMorphine Semisynthetic Derivatives
Methylation of 3 phenolic hydroxy group in morphine yield ______
💡Correct Answer: Option C (Codeine)
Codeine is chemically 3-O-methylmorphine, formed by the selective O-methylation of the phenolic hydroxyl group at carbon C-3 of morphine.
Q88
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsMAOI Adverse Drug Interactions
Which class show adverse reaction hypertensive cheese effect.
💡Correct Answer: Option A (MAO Inhibitors)
Non-selective Monoamine Oxidase (MAO) Inhibitors block the intestinal and hepatic breakdown of dietary Tyramine (found in aged cheese, wine, yeast), triggering dangerous hypertensive crisis ('Cheese Effect').
Q89
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsCentral Nervous System Drugs Matching
Match the columns: Drug: i. Ethosuximide ii. Fluphenazine iii. Thiopental iv. Trimethadione
💡Correct Answer: Option A (i-4, ii-3, iii- 2, iv-1)
i -> 4 (Ethosuximide: Succinimide antiepileptic), ii -> 3 (Fluphenazine: Phenothiazine antipsychotic), iii -> 2 (Thiopental: Thiobarbiturate IV anesthetic), iv -> 1 (Trimethadione: Oxazolidinedione antiepileptic). Correct match: i-4, ii-3, iii-2, iv-1.
Q90
Medicinal Chemistry, Pharmacology, SAR & TherapeuticsBeta-Blockers Metabolism (Esmolol)
Assertion: Esmolol is shortest acting β blocker Reason: Esmolol contains metabolically labile ester group. Which of the following is correct?
💡Correct Answer: Option D (Both A and R are true)
Both Assertion and Reason are true and Reason explains Assertion: Esmolol has an ultra-short elimination half-life (t1/2≈9 minutes) because its molecular structure contains an aliphatic methyl ester linkage that is rapidly hydrolyzed by red blood cell cytosol esterases.
Q91
Pharmacognosy, Phytochemistry & General AwarenessAntihypertensive Herbal Drugs
Drug used to hypertension
💡Correct Answer: Option D (Rauwolfia)
Rauwolfia (Rauwolfia serpentina, Indian Snakeroot), containing the indole alkaloid Reserpine which depletes vesicular catecholamines, is used as an antihypertensive and tranquilizer.
Q92
Pharmacognosy, Phytochemistry & General AwarenessSenna Phytochemistry
Chief constituent present in senna is
💡Correct Answer: Option C (Sennosides)
The primary active laxative principles in Senna leaves and pods are dianthrone anthraquinone glycosides known as Sennosides (Sennosides A, B, C, and D).
Q93
Pharmacognosy, Phytochemistry & General AwarenessBotanical Families
Senna belongs to the family of
💡Correct Answer: Option A (Leguminosae)
Senna (Cassia senna / Cassia angustifolia) belongs to the family Leguminosae (subfamily Caesalpiniaceae / Fabaceae).
Q94
Pharmacognosy, Phytochemistry & General AwarenessBotanical Families
Digitalis belongs to family ______
💡Correct Answer: Option C (Scrophulariaceae)
Digitalis (Digitalis purpurea, Foxglove) traditionally belongs to the plant family Scrophulariaceae (reclassified into Plantaginaceae).
Q95
Pharmacognosy, Phytochemistry & General AwarenessNux Vomica Alkaloid Assay
Amount of strychnine contained by nuxvomica is
💡Correct Answer: Option D (1.25%)
According to pharmacopoeial monographs, dried ripe seeds of Strychnos nux-vomica contain approximately 2.6% to 3.0% total alkaloids, of which at least 1.25% is Strychnine.
Q96
Pharmacognosy, Phytochemistry & General AwarenessIpecacuanha Active Principles
Which compound in Ipecacuanha is primarily responsible for its emetic action?
💡Correct Answer: Option C (Emetine)
The isoquinoline alkaloid Emetine (along with cephaeline) present in Ipecacuanha root acts locally on gastric mucosa and centrally on the chemoreceptor trigger zone (CTZ) to induce emesis (vomiting).
Q97
Pharmacognosy, Phytochemistry & General AwarenessHerbal Adulteration
Which of the following is a common adulterant of Ceylon cinnamon?
💡Correct Answer: Option A (Cassia cinnamon)
Cassia bark (Cinnamomum cassia / Chinese cinnamon) is the most common commercial adulterant and substitute used for authentic Ceylon cinnamon (Cinnamomum zeylanicum).
Q98
Pharmacognosy, Phytochemistry & General AwarenessCinnamon Bark Pharmacognosy
Fracture of cinnamon bark is
💡Correct Answer: Option D (Splintery)
The pharmacognostic fracture characteristic of authentic Cinnamomum zeylanicum bark is Splintery (short and splintery in the outer part, fibrous inside).
Q99
Pharmacognosy, Phytochemistry & General AwarenessBotanical Sources
Nuxvomica is biologically obtained from
💡Correct Answer: Option A (Seed of Strychnos nux vomica)
Nux Vomica consists of the dried ripe Seeds of Strychnos nux-vomica Linn. (Family: Loganiaceae).
Q100
Pharmacognosy, Phytochemistry & General AwarenessSenna Botanical Sources
Tinnevelly senna is obtained from
💡Correct Answer: Option B (Cassia angustifolia)
Tinnevelly Senna (Indian Senna) consists of the dried leaflets of Cassia angustifolia Vahl (Alexandrian Senna is obtained from Cassia acutifolia).
Q101
Pharmacognosy, Phytochemistry & General AwarenessOpium Morphine Content
Opium contains ______ % of morphin
💡Correct Answer: Option B (9%)
According to Indian Pharmacopoeia and international standards, crude raw Opium latex contains not less than 9.5% to 10% (approx 9% to 12%) of anhydrous Morphine.
Q102
Pharmacognosy, Phytochemistry & General AwarenessRauwolfia Microscopy
Stratified cork is characteristic of
💡Correct Answer: Option D (Rauwolfia)
A transverse section of Rauwolfia serpentina root microscopically exhibits distinctive Stratified Cork consisting of alternating bands of suberized and lignified cells.
Q103
Pharmacognosy, Phytochemistry & General AwarenessMicroscopic Calcium Oxalate Crystals
Rhombohedral crystals are characteristics of ______
💡Correct Answer: Option B (Kurchi bark)
Transverse sections of Kurchi bark (Holarrhena antidysenterica) show abundant diagnostic Rhombohedral and prism crystals of calcium oxalate in its parenchymatous cells.
Q104
Pharmacognosy, Phytochemistry & General AwarenessTrichomes in Pharmacognosy
Lignified trichomes present in ______
💡Correct Answer: Option C (Nux vomica)
The seed coat (testa) of Nux Vomica is covered with dense, silky, appressed Lignified Trichomes with collapsed bent bases.
Q105
Pharmacognosy, Phytochemistry & General AwarenessStomatal Types in Pharmacognosy
Anisocytic stomata are present in ______
💡Correct Answer: Option D (Belladonna)
Leaves of Atropa belladonna (and Solanaceae) characteristically possess Anisocytic (unequal-celled / cruciferous) stomata, where the guard cells are surrounded by three subsidiary cells, one of which is distinctly smaller.
Q106
Pharmacognosy, Phytochemistry & General AwarenessAloe Vera Phytochemistry
Chemical constituents of Aloe except ______
💡Correct Answer: Option D (Eugenol)
Eugenol is a phenylpropanoid volatile oil found in Clove and Cinnamon. Aloe vera contains anthraquinone glycosides Barbaloin, Isobarbaloin, and Aloe-emodin.
Q107
Pharmacognosy, Phytochemistry & General AwarenessTulsi Botanical Source
Biological source of Tulsi is
💡Correct Answer: Option B (Ocimum sanctum)
Holy Basil (Tulsi) consists of the fresh and dried leaves of Ocimum sanctum Linn. (synonym: Ocimum tenuiflorum, Family: Lamiaceae).
Q108
Pharmacognosy, Phytochemistry & General AwarenessCinchona Chemical Tests
Name the drug for which Thalloquin test is performed
💡Correct Answer: Option C (Cinchona)
The Thalleioquin test (treating sample with bromine water and dilute ammonia to yield an emerald-green color) is the specific diagnostic test for Quinine and Quinidine in Cinchona bark.
Q109
Pharmacognosy, Phytochemistry & General AwarenessOpium Plant Part
Which part of plant is used for medicinal value in case of opium
💡Correct Answer: Option B (Dried latex)
Opium is the Dried Latex / air-dried milky exudate obtained by incising the unripe capsule fruit of Papaver somniferum.
Q110
Pharmacognosy, Phytochemistry & General AwarenessHerbal Synonyms
Ma Huang is synonym for ______
💡Correct Answer: Option B (Ephedra)
Ma Huang is the traditional Chinese synonym for Ephedra (Ephedra sinica / Ephedra gerardiana).
Q111
Pharmacognosy, Phytochemistry & General AwarenessIndian Constitution Article 33
Which among the following authorities decides, how far the fundamental rights can apply to the members of the armed forces in India?
💡Correct Answer: Option B (Parliament of India)
Under Article 33 of the Constitution of India, the Parliament of India alone has the exclusive constitutional power to restrict or abrogate the application of Fundamental Rights to members of the Armed Forces and Police forces.
Q112
Pharmacognosy, Phytochemistry & General AwarenessQuantum Physics (de Broglie Relation)
What is the relation between mass and wavelength of any matter, as per de Broglie's relation?
💡Correct Answer: Option B (Both are inversely proportional)
De Broglie's matter-wave equation is λ=m⋅vh. Hence, de Broglie wavelength is Inversely Proportional to mass (m) for a given velocity.
Q113
Pharmacognosy, Phytochemistry & General AwarenessHistory and Forts of J&K
Hari parbat was built by
💡Correct Answer: Option D (Atta Mohammed Khan)
The present historic Hari Parbat Fort (Durrani Fort / Qila Koh-e-Maran in Srinagar) was constructed in 1808 by Afghan governor Atta Mohammed Khan (the original outer rampart wall was built by Mughal Emperor Akbar in 1590).
Q114
Pharmacognosy, Phytochemistry & General AwarenessOlympic Awards
The "Pierre de Coubertin Medal" is awarded for the excellence in which field?
💡Correct Answer: Option B (Sports)
The Pierre de Coubertin Medal (also known as the True Spirit of Sportsmanship medal) is awarded by the International Olympic Committee to athletes who demonstrate exceptional sportsmanship in Sports.
Q115
Pharmacognosy, Phytochemistry & General AwarenessFive Year Plans & Blue Revolution
Blue revolution was first launched in India during which of the Five Year Plan?
💡Correct Answer: Option C ($7^{\text{th}}$ Five Year Plan)
The Blue Revolution (Neel Kranti Mission for aquaculture and fisheries development) was officially launched in India during the 7th Five Year Plan (1985–1990) through the Fish Farmers Development Agency (FFDA).
Q116
Pharmacognosy, Phytochemistry & General AwarenessDesert Development Programme
Consider the following states: 1. Rajasthan 2. Gujarat 3. Jammu & Kashmir 4. Himachal Pradesh Desert Development programme was started in which of the above states?
💡Correct Answer: Option D (1, 2, 3 & 4)
The Desert Development Programme (DDP) was launched in 1977–78 covering both hot desert areas (Rajasthan, Gujarat, Haryana) and cold desert areas (Jammu & Kashmir / Ladakh, Himachal Pradesh). All 1, 2, 3, and 4 were covered.
Q117
Pharmacognosy, Phytochemistry & General AwarenessIndian Manufacturing & Standards
Which company has launched the first Made-in-India helmet to meet Europe's ECE 22.06 standard?
💡Correct Answer: Option B (Steelbird)
Steelbird Hi-Tech India launched the 'Ignite' helmet range, making it the first Indian manufacturer to meet the stringent European ECE 22.06 safety standard.
Q118
Pharmacognosy, Phytochemistry & General AwarenessMacroeconomics Concepts
Which of the following best describes the Phillips Curve in macroeconomics?
💡Correct Answer: Option A (It shows the trade off between inflation and unemployment)
The Phillips Curve (A.W. Phillips, 1958) is an economic concept stating that inflation and unemployment have a stable, inverse relationship (trade-off).
Q119
Pharmacognosy, Phytochemistry & General AwarenessBanking & NBFC Regulations
Which type of NBFC activities are not eligible for bank credit?
💡Correct Answer: Option A (Investments in shares and debentures)
Under Reserve Bank of India (RBI) prudential guidelines, commercial bank financing is strictly prohibited for NBFC activities involving investments in shares, debentures, and speculative real estate.
Q120
Pharmacognosy, Phytochemistry & General AwarenessInternational Trade Economics
Consider a scenario in which a small country imposes a tariff on a product. Which of the statements below is false?
💡Correct Answer: Option B (The surplus of the producer of the goods will decrease.)
When a tariff is imposed on imported goods, domestic prices rise, causing domestic Producer Surplus to INCREASE (not decrease). Thus, Statement B ('The surplus of the producer of the goods will decrease') is FALSE.
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About JKSSB Drug Control Officer 2025 Previous Year Paper
This page provides the full solved question paper for the JKSSB Drug Control Officer examination conducted in 2025. Every MCQ is presented with verified answer keys and detailed bilingual explanations to support concept building.
Key subjects covered in this paper include Pharmaceutical Jurisprudence, Drug Acts & Regulatory Affairs, Pharmaceutics, Dosage Forms & Biopharmaceutics, Pharmaceutical Analysis, Limit Tests & Quality Control, Medicinal Chemistry, Pharmacology, SAR & Therapeutics, Pharmacognosy, Phytochemistry & General Awareness. Practicing authentic previous year questions is the proven way to master question patterns and improve accuracy for upcoming exams across Jammu & Kashmir.